Adderall XR beads removed from the capsule
Adderall has been used recreationally by all common routes of administration. Snorting Adderall (insufflation) is not an uncommon way to abuse the drug.
Adderall is comprised of mixed amphetamine salts. Specifically, Adderall contains dextroamphetamine and levoamphetamine in a ratio of 3:1.
Unsurprisingly, the effects of snorting Adderall are a more pronounced version of orally consumed Adderall. Snorting Adderall results in a faster onset of the effects, since the nasal cavity is close to the brain, and amphetamine can readily diffuse across the blood brain barrier. Theoretically, snorting Adderall bipasses the first-pass effect, where the liver metabolizes a substance before it is able to enter systemic circulation.
The concensus is that snorting Adderall does not significantly increase the bioavailability of the drug and hence has little benefit with added downsides.
Adderall has a "sweet" taste like sugar, and burns the nose slightly. Adderall insufflation also causes a rebound increase in mucus production the next day after insufflation. This occurs because amphetamines, like ephedrine, are decongestants that promote norepinephrine release which decreases mucus output. However, after the drug is cleared from your system, rebound congestion of the nasal cavity occurs, since the body is always trying to achieve homeostasis.
One redditor offered the following advice about Adderall insufflation:
If you plan on using frequently, stay away from snorting. The oral bioavailability for amphetamine is relatively high anyways and the extra rush is not worth the deviated septum. I had a deviated septum (non drug related) and not only did it completely suck in just about every nose-related instance in my life, but the surgery for it is a bitch.