You asked: Does sodium valproate help depression?

Is sodium valproate good for depression?

Valproate is a mood stabilizer medication that works in the brain. It is approved for the treatment of mania associated with bipolar disorder (also known as manic depression), seizures (epilepsy), and migraine headaches. Bipolar disorder involves episodes of depression and/or mania.

Is sodium valproate good for anxiety?

The first and only double-blind, placebo-controlled randomized study that investigated the effectiveness of valproate in the treatment of anxiety disorders in 68 patients with generalized anxiety disorder reported that valproate significantly reduced anxiety symptoms compared to placebo [8.

Is sodium valproate an antidepressant?

Sodium valproate as an antidepressant.

Does valproic acid help with depression?

Valproic acid may be particularly helpful for patients who have symptoms of mania and depression occurring at the same time (a ‘mixed’ episode) or who have more than four mood episodes per year (this is called ‘rapid cycling’). This medication may also specifically target aggressive or impulsive behavioural problems.

What is the safest mood stabilizer?

The safest and most efficacious mood stabilizer combinations appear to be the mixtures of anticonvulsants and lithium, particularly valproate plus lithium.

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What are the main side effects of sodium valproate?

Common side effects

  • stomach pain, feeling or being sick (nausea or vomiting)
  • diarrhoea.
  • dry or sore mouth, or swollen gums.
  • shakes (tremors) in a part of your body, or unusual eye movements.
  • feeling tired or sleepy.
  • headache.
  • weight gain.
  • thinning hair, or changes to the colour or texture of your hair.

How quickly does valproate work?

Sodium valproate may take several days to show an initial effect and in some cases may take from two to six weeks for maximum effect. Treatment is started with low doses and may be increased over a couple of weeks according to your child’s response.

Is sodium valproate a sedative?

Sodium valproate is a commonly used antiepileptic drug (AED) for control of a broad range of seizures. Adverse drug reactions (ADR) due to sodium valproate range from sedation to nausea, vomiting, weight gain, idiosyncratic adverse effects like hepatotoxicity and life threatening conditions like pancreatitis.

How do I know if I need a mood stabilizer?

Your doctor may prescribe mood stabilisers if you have an episode of mania, hypomania or depression that changes or gets worse suddenly. This is called an acute episode. Some people need to take mood stabilisers as a long-term treatment to stop this from happening.

How does valproic acid make you feel?

Valproic acid may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you notice any of these side effects, tell your doctor right away.

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Does sodium valproate cause depression?

Conclusion. From our case series, it is suggested that the higher doses of valproate, such as those used in the treatment of acute mania, may cause a depressive switch following remission from the manic episode.

Is epilim a mood stabilizer?

valproate (Depakote, Epilim) may be prescribed to treat mania if you haven’t responded well to lithium. But you should not be prescribed it if you are pregnant or could become pregnant. See our page on taking mood stabilisers during pregnancy or breastfeeding to find out more.

When should I stop taking valproic acid?

Do not stop taking valproic acid suddenly, unless your doctor tells you to. You’re unlikely to get any extra symptoms when you stop taking this medicine. However if you’re taking it for bipolar disorder or to prevent migraine, your condition could get worse for a short time after you stop taking the medicine.

Is valproic acid an antipsychotic?

Mood stabilizers (e.g., valproic acid) and antipsychotic drugs (APDs) are commonly co-administered in the treatment of bipolar disorder and schizophrenia.

Is 500mg of Depakote a lot?

Depakote ER is indicated for prophylaxis of migraine headaches in adults. The recommended starting dose is 500 mg once daily for 1 week, thereafter increasing to 1000 mg once daily.

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