Abstract: Quetiapine, an atypical antipsychotic, has been extensively used in patients with bipolar disorder. Overdose of quetiapine can result in severe complications, such as coma, seizure, respiratory depression, arrhythmia, and even death.
Does Seroquel cause breathing problems?
Quetiapine can cause a severe allergic reaction. Symptoms can include: trouble breathing.
Does Seroquel suppress breathing?
You may experience an increase in side effects such as excessive sedation, slowed rate of breathing, confusion, agitation, or loss of coordination.
Can antipsychotics cause respiratory depression?
As suggested, inhibition of serotonergic, dopaminergic, and histaminergic receptors by antipsychotics may cause improper respiratory muscle activity9,10,12 or central respiratory depression.
Why is Seroquel bad for you?
Quetiapine can cause significant weight gain, even when used in small to moderate doses for sleep. It has also been associated with increased blood glucose (sugar) and dyslipidaemia (an imbalance of fats circulating in the blood). These increase the risk of developing type 2 diabetes and heart disease.
What can replace Seroquel for sleep?
Conclusions: With respect to total sleep time and nighttime awakenings, trazodone was a more effective alternative than quetiapine. However, patients receiving trazodone experienced more gastrointestinal patient-reported side effects.
Why is Seroquel not recommended for sleep?
It works by altering the levels of certain chemical messengers called neurotransmitters in your brain — in particular, serotonin and dopamine. Although it has a sedative effect, quetiapine isn’t recommended for insomnia.
Can Seroquel cause manic episodes?
Quetiapine has a moderate anticholinergic effect that may affect cognitive functions and lead to delirium in at-risk individuals . In addition, quetiapine may induce hypothyroidism, which can clinically manifest as a hypomanic/manic episode in some patients [14, 15].
Can Seroquel make you psychotic?
The FDA issued a black box warning on all antipsychotic drugs, including Seroquel, due to the increased risk of death in elderly patients with dementia-related psychosis.
Can lorazepam cause respiratory depression?
Use of benzodiazepines, including lorazepam, both used alone and in combination with other CNS depressants, may lead to potentially fatal respiratory depression.