Several medications may precipitate or aggravate RLS, including nonprescription allergy and cold medications that contain antihistamine (Benadryl), most antidepressants (Elavil, Prozac), and major tranquilizers (Haldol, Mellaril, Thorazine).
Which antidepressants cause restless legs?
Among the various antidepressants, mirtazapine may be associated with higher rates of restless legs syndrome and periodic limb movements. One small study of normal volunteers suggested that venlafaxine may be associated with an increase in restless legs syndrome symptoms and periodic limb movements.
Why do SSRIs cause restless leg syndrome?
Most antidepressant medications work by increasing availability of certain brain chemicals called neurotransmitters –particularly serotonin. Unfortunately, increasing serotonin worsens symptoms of RLS.
Can SSRI cause restless legs?
Certain antidepressant drugs, including the selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), may induce or exacerbate RLS.
How do I stop restless legs from medication?
During an episode of restless legs syndrome, the following measures may help relieve your symptoms:
- massaging your legs.
- taking a hot bath in the evening.
- applying a hot or cold compress to your leg muscles.
- doing activities that distract your mind, such as reading or watching television.
What medications aggravate restless leg syndrome?
certain medications that may aggravate RLS symptoms, such as antinausea drugs (e.g. prochlorperazine or metoclopramide), antipsychotic drugs (e.g., haloperidol or phenothiazine derivatives), antidepressants that increase serotonin (e.g., fluoxetine or sertraline), and some cold and allergy medications that contain …
How long can restless leg syndrome last?
How long will restless legs syndrome last? Symptoms of primary or idiopathic RLS typically worsen over time, but, for some people, weeks or months may pass without any symptoms. If the RLS stems from a condition, illness, pregnancy, or medication, it may go away as soon as the trigger has gone.
How do you sleep with restless legs?
8 Nighttime and Sleep Tips to Ease Restless Legs Syndrome
- Regular, moderate exercise may help you sleep better. …
- Warm up to bedtime. …
- Take it easy! …
- Sleep a little better tonight by avoiding nicotine and caffeine close to bedtime.
- You’ll sleep better, and feel better, if you maintain a regular sleep schedule.
Is there any new treatment for RLS?
The FDA has approved gabapentin enacarbil for use in RLS, preferring it over standard gabapentin because it has fewer side effects. Another similar drug, pregabalin17, also shows promising results for RLS symptoms and sleep quality, and carries a low risk of side effects.
Does hydroxyzine worsen restless leg syndrome?
Many anti-nausea drugs (trimethobenzamide, prochlorperazine, promethazine, hydroxyzine, meclizine, and metoclopramide) block the dopamine system and thus may worsen RLS .
Does Wellbutrin help with restless leg syndrome?
Bupropion, an inhibitor of dopamine and noradrenalin reuptake, is an antidepressant that modulates dopaminergic systems. The authors report that a low dose of bupropion rapidly and completely ameliorated RLS symptoms in 3 depressed patients within a few days of the initiation of treatment.
Why does Benadryl make my legs restless?
In particular, anti-nausea drugs and sedating antihistamines (like Benadryl) block the brain’s dopamine receptors, causing restless legs symptoms.