What antipsychotics are given as depot?
Antipsychotic depot injections
|Antipsychotic depot injections||Preparations|
|Flupentixol decanoate||20mg/ml, 40mg/2ml, 50mg/0.5ml, 100mg/1ml, 200mg/ml injection|
|Haloperidol decanoate||50mg/ml, 100mg/ml injection|
|Paliperidone palmitate 1-monthly(Xeplion®)||50mg, 75mg, 100mg, 150mg pre-filled syringes|
Which atypical antipsychotics are available as injectables?
Second-generation atypical antipsychotics available for long-acting injection include:
- risperidone (Perseris Kit, Indivior Inc.; Risperdal Consta, Janssen),
- olanzapine pamoate (Zyprexa Relprevv, Eli Lilly),
- paliperidone palmitate in two formulations (Invega Sustenna, Janssen; Invega Trinza, Janssen); and.
What drug is Depot?
A depot injection is a slow-release form of medication. The injection uses a liquid that releases the medication slowly, so it lasts a lot longer. Depot injections can be used for various types of drug, including some antipsychotics.
What is the advantage of injectable antipsychotics?
Benefits of use of long acting injectable (LAI) antipsychotics: Increased medication adherence and steady blood level balanced with decreased need to take daily oral doses; clinic visit or nursing visit for injection allows for consistent relationship and monitoring by clinicians.
What is the fastest acting antipsychotic?
Intramuscular olanzapine has shown faster onset of action, greater efficacy and fewer adverse effects than haloperidol or lorazepam in the treatment of acute agitation associated with schizophrenia, schizoaffective disorder, bipolar mania and dementia.
How long does it take for antipsychotics to wear off?
Antipsychotic discontinuation syndrome symptoms generally appear within the first few days after you stop use or significantly reduce use. The symptoms tend to be the most severe around the one-week mark and subside after that.
What is the safest medication for schizophrenia?
Clozapine and olanzapine have the safest therapeutic effect, while the side effect of neutropenia must be controlled by 3 weekly blood controls. If schizophrenia has remitted and if patients show a good compliance, the adverse effects can be controlled.
What happens if I take antipsychotics?
Side-effects of typical antipsychotics vary depending on the drug and may include drowsiness, agitation, dry mouth, constipation, blurred vision, emotional blunting, dizziness, stuffy nose, weight gain, breast tenderness, liquid discharge from breasts, missed periods, muscle stiffness or spasms.
Do injectable antipsychotics have less side effects?
Although not by as wide of a margin, more respondents who preferred long-acting injections versus pills also cited fewer side effects (37% vs 10%), better efficacy for symptom control (37% vs 8%), and less pain/sudden symptoms (38% vs 18%) as other reasons for their preference.