The main difference between the medications is that Wellbutrin SR is the sustained-release version, whereas Wellbutrin XL is the extended-release version. The XL version is released more slowly into your body, which means it remains in your system longer.
Which is better Wellbutrin SR or XL?
Wellbutrin SR and Wellbutrin XL are both effective for treating depression. Their uses and differences in dosing hold the most weight when choosing between the two. In a clinical study comparing bupropion SR and bupropion XL, those taking the once-daily bupropion XL experienced lower rates of depression and relapse.
Can you switch from Wellbutrin SR to XL?
Once these drugs are stable in your system, they are designed to work at the same strength. You should not change between Wellbutrin XL and SR on your own. Your doctor may switch formulations depending on your diagnosis and response to treatment.
How long does Wellbutrin SR last?
At between 33 to 37 hours, the half-life of Wellbutrin is exceptionally long for an antidepressant. As with most medications, do not abruptly stop taking Wellbutrin without the assistance from your doctor because of the risk of side effects from withdrawal.
Is Wellbutrin SR better than XL for weight loss?
Wellbutrin XL and Wellbutrin SR are different formulations of the antidepressant bupropion. Both Wellbutrin XL and Wellbutrin SR may cause weight gain or weight loss, but weight loss is more common. Not everyone taking these drugs will experience a change in weight.
Does bupropion give you energy?
On the other hand, bupropion does stand out among the antidepressants as having a positive effect on energy. When patients are up and active during the day, they are likely to sleep better at night.
How much weight did you lose on Wellbutrin XL?
Wellbutrin XL (bupropion): “I used Wellbutrin XL for two years, and in conjunction with sensible eating and a walking regimen, lost 75 pounds.
How quickly does Wellbutrin SR work?
It often takes 6-8 weeks before you notice an improvement in your mood or regain interest in activities you enjoy. Wellbutrin XL and SR both work the same way.
Why was Wellbutrin discontinued?
The decision is based on an FDA study that found that the extended release (XL) form of bupropion — Budeprion XL — at the 300 milligram (mg) dose was not bioequivalent to brand-name Wellbutrin XL at the same dose, suggesting that it may not be as safe and effective.
Does Wellbutrin SR help you lose weight?
Bupropion seems to be effective for weight-loss maintenance as well. A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012).
How does Wellbutrin make you feel?
Shortly after beginning Wellbutrin, some people may have symptoms such as: anxiety. feeling restless. agitation.
When is the best time to take Wellbutrin?
The sustained-release tablet (Wellbutrin SR, Zyban) is usually taken twice a day, with doses at least 8 hours apart. The extended-release tablet (Aplenzin, Wellbutrin XL) is usually taken once daily in the morning; doses of the extended-release tablet should be taken at least 24 hours apart.