What Is Ephedrine? Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis.
What does ephedrine sulfate treat?
Ephedrine Sulfate Injection, USP is indicated in the treatment of allergic disorders, such as bronchial asthma. The drug has long been used as a pressor agent, particularly during spinal anesthesia when hypotension frequently occurs.
How does ephedrine affect the body?
Because of its direct sympathomimetic effects, ephedrine can increase heart rate, contractility, cardiac output, and peripheral resistance. Thus, increases in both heart rate and blood pressure are common observations after ephedrine ingestion.
What does ephedrine stimulate?
Introduction. Ephedrine is a sympathomimetic found in plants of the Ephedra genus. Often referred to as a “mixed acting” sympathomimetic, ephedrine causes the release of norepinephrine from storage vesicles in sympathetic neurons and directly stimulates alpha and beta adrenoceptors.
Does ephedrine lower blood pressure?
Ephedrine is a central nervous system stimulant used to treat low blood pressure problems (hypotension).
How fast does ephedrine sulfate work?
Onset with intravenous use is fast, while injection into a muscle can take 20 minutes, and by mouth can take an hour for effect. When given by injection it lasts about an hour and when taken by mouth it can last up to four hours.
When is ephedrine given?
USES: Ephedrine injection is a central nervous system stimulant used to treat low blood pressure (hypotension) during certain surgical procedures, severe allergic-type reactions (e.g., bronchospasm or bronchial asthma), certain heart rhythm problems (e.g., Stokes-Adams syndrome), narcolepsy, and myasthenia gravis.
What are the long term effects of ephedrine?
Ephedra can cause severe life-threatening or disabling conditions in some people. Ephedra use is linked to high blood pressure, heart attacks, muscle disorders, seizures, strokes, irregular heartbeat, loss of consciousness, and death.
How much weight can you lose with ephedrine?
In addition to the short-term changes in metabolism, some studies show that ephedrine can promote weight and fat loss over longer time periods. In five studies of ephedrine compared to a placebo, ephedrine led to weight loss of 3 pounds (1.3 kg) per month more than a placebo — for up to four months ( 10 , 11 ).
Is it illegal to have ephedrine?
While FDA-approved ephedrine and pseudoephedrine products remain available “behind the counter” as drugs (in some asthma medications, for instance, and in cold medicine, like Sudafed), ephedrine supplements are banned.
Why is ephedrine controlled?
Conclusions: Tighter control of all ephedrine products, drugs and dietary supplements alike, might have prevented adverse outcomes and allowed this substance to remain available in a safer manner. Stringent regulation of all ephedrine products is necessary to prevent misuse and to protect the public’s health.
Does ephedrine increase dopamine?
Ephedrine, which has been used as a decongestant and weight loss agent, causes both central serotonin and dopamine (DA) release (Bowyer et al., 2000).
What medicines contain ephedrine?
Common brands containing ephedrine:
Bronkaid® Primatene® Tablets. Store Brands (ex: Walmart’s “Equate” store brand or CVS Health store brand)