Lamotrigine is an important medication option for the treatment of bipolar disorders. However, many clinicians also use it in patients with a (unipolar) depressive disorder who have not responded adequately to conventional antidepressants.
Is lamotrigine used for major depression?
Conclusions: Our results suggest that lamotrigine could be useful as augmentation of antidepressants for treatment-resistant unipolar depression. Also, lamotrigine may accelerate the onset of antidepressant action, and therefore might be useful in treatment of major depression in general.
What is used to treat unipolar depression?
Common medications and treatment options for unipolar depression include: Tricyclic antidepressant (TCAs), such as imipramine and nortriptyline, to improve mood. Selective Serotonin Reuptake Inhibitors (SSRIs), such as Prozac, Luvox, Paxil, or Zoloft to improve mood.
Do mood stabilizers help unipolar depression?
The oldest and best mood stabilizer is lithium carbonate (lithium). Although this medication is primarily used to treat bipolar disorders, lithium can also be effective in alleviating unipolar depressive symptoms.
What is the most effective treatment for unipolar depression?
Efficacy of antidepressants plus psychotherapy — For the initial treatment of unipolar major depression, randomized trials indicate that the combination of pharmacotherapy and psychotherapy (eg, cognitive-behavioral therapy or interpersonal psychotherapy) is more efficacious than either pharmacotherapy alone or …
Does Lamictal make you feel happy?
Lamotrigine is the only mood stabilizer that calms mood swings by lifting the depression rather than suppressing the mania, says Dr. Aiken. “That makes it a great choice for the bipolar spectrum, where the depressive symptoms usually outweigh the manic ones. Its greatest benefit is in prevention.
Can lamotrigine worsen anxiety?
Know that you may experience changes in your mental health. This medication may cause thoughts of suicide, panic attacks, agitation, new or worsening irritability, restlessness, anxiety, dangerous impulses, depression, insomnia, aggressive behavior, abnormally excited moods and other unusual changes in mood.
What is the best medicine for depression?
When treating depression, several drugs are available. Some of the most commonly used include: Selective serotonin reuptake inhibitors (SSRIs), such as citalopram (Celexa), escitalopram oxalate (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine HRI (Paxil), and sertraline (Zoloft).
What is the safest mood stabilizer?
The safest and most efficacious mood stabilizer combinations appear to be the mixtures of anticonvulsants and lithium, particularly valproate plus lithium.
What mood stabilizers cause weightloss?
Topiramate led to substantial weight loss in patients with bipolar disorders in these studies. The efficacy of topiramate as an adjunct treatment in patients with mood disorders has been demonstrated.
What mood stabilizers are used to treat bipolar?
You’ll typically need mood-stabilizing medication to control manic or hypomanic episodes. Examples of mood stabilizers include lithium (Lithobid), valproic acid (Depakene), divalproex sodium (Depakote), carbamazepine (Tegretol, Equetro, others) and lamotrigine (Lamictal).
Is unipolar the same as depression?
The unipolar designation indicates that the depression does not alter between the two mood states. Additionally referred to as major depressive disorder (MDD), major depression, or clinical depression, this mood disorder is a medical condition that can impact many critical areas of one’s life.
Can you ever be cured from depression?
While depression can be treated, and symptoms can be alleviated, depression cannot be “cured.” Instead, remission is the goal. There’s no universally accepted definition of remission, as it varies for each person. People may still have symptoms or impaired functioning with remission.
What SSRI do I take for depression?
Switch to a different kind of antidepressant that is not an SSRI, such as bupropion (Wellbutrin®), desvenlafaxine (Pristiq®), duloxetine (Cymbalta®), or venlafaxine (Effexor®). Add an antipsychotic medicine to your SSRI, such as aripiprazole (Abilify®), olanzapine (Zyprexa®), or quetiapine XR (Seroquel XR®).