Conclusions: Although neutropenia is not a common side effect of quetiapine, physicians should be cautious about its presentation and associated risk factors. Hepatic dysfunction may be one of the possible risk factors, and concomitant fever may be a diagnostic marker for adverse reaction to quetiapine.
Can Seroquel lower white blood cells?
Quetiapine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting.
Does Seroquel cause leukopenia?
The manufacturers of quetiapine state that its risk is approximately 2% . In a literature review of 21 cases of leukopenia, neutropenia, and thrombocytopenia caused by quetiapine, only one case, with a daily regimen of 50 mg of quetiapine, caused clinically significant low WBCs.
Can antipsychotics cause low white blood cell count?
Reduced white blood cells
Taking antipsychotics may cause a reduction in your white blood cells.
What psychiatric drugs cause neutropenia?
Of drugs encountered in psychiatry, antipsychotics including clozapine (risk of agranulocytosis approximately 0.8%, predominantly in the first year of treatment) and phenothiazines (chlorpromazine agranulocytosis risk approximately 0.13%), and antiepileptics (notably carbamazepine, neutropenia risk approximately 0.5%) …
Does Seroquel cause low blood sugar?
Quetiapine is known to be able to induce mild hypoglycemia in patients without diabetes. We report on our experience treating an older individual without diabetes who developed severe hypoglycemia as a result of administration of quetiapine.
Can Seroquel affect blood test?
Occasionally, Seroquel may be associated with changes in your liver function or blood (eg blood fat levels such as cholesterol or triglycerides, blood sugar levels, blood pressure, thyroid hormone levels, white blood cells). These can only be found when your doctor does tests from time to time to check your progress.
What are the side effects of taking quetiapine?
Quetiapine may cause side effects. Tell your doctor if any of these symptoms or those listed in the SPECIAL PRECAUTIONS section are severe or do not go away:
- dizziness, feeling unsteady, or having trouble keeping your balance.
- pain in the joints, back, neck, or ears.
- dry mouth.
What can low white blood cells mean?
A low white blood cell count usually is caused by: Viral infections that temporarily disrupt the work of bone marrow. Certain disorders present at birth (congenital) that involve diminished bone marrow function. Cancer or other diseases that damage bone marrow.
What is absolute neutrophil count?
A measure of the number of neutrophils in the blood. Neutrophils are a type of white blood cell. They help the body fight infection. An absolute neutrophil count may be used to check for infection, inflammation, leukemia, and other conditions.
What is the most troublesome side effect of antipsychotic medications?
All antipsychotic medications are associated with an increased likelihood of sedation, sexual dysfunction, postural hypotension, cardiac arrhythmia, and sudden cardiac death. Primary care physicians should understand the individual adverse effect profiles of these medications.
What is the strongest antipsychotic?
Clozapine, which has the strongest antipsychotic effect, can cause neutropenia. A problem in the treatment of schizophrenia is poor patient compliance leading to the recurrence of psychotic symptoms.
Which antipsychotic is least likely to cause neutropenia?
TO THE EDITOR: Antipsychotic drugs can induce neutropenia, which can be followed by agranulocytosis and even be fatal if drug therapy is not interrupted. Olanzapine and risperidone are newer antipsychotic drugs that tend to reduce the risk of hematotoxicity.