Our review supports the conclusion that antidepressants generally do more harm than good by disrupting a number of adaptive processes regulated by serotonin. However, there may be specific conditions for which their use is warranted (e.g., cancer, recovery from stroke).
Are antidepressants really that bad?
The range of their uses has expanded from depression to anxiety, obsessive-compulsive disorder, eating disorders, and many other psychiatric conditions. These types of antidepressants are generally safe, but no medical treatment is without risk.
Why you should avoid antidepressants?
They are at greater risk for all the acute side effects I’ve already listed, as well as increased risk of relapse, cognitive impairment, secondary diagnosis and medication treatments (first a depression diagnosis followed by a bipolar one), and recurrent hospitalization.
What are the disadvantages of antidepressants?
Common side effects in this class may include:
- blurred vision.
- heart toxicity in those at risk.
- dry mouth.
- fatigue or drowsiness.
- increased heart rate.
- increased appetite and weight gain.
What is the most successful antidepressant?
Antidepressants sold in the United States that the study found to be most effective included: Amitriptyline.
When the researchers checked which depression drugs were tolerated the best, these topped the list:
- Celexa (citalopram)
- Lexapro (escitalopram)
- Prozac (fluoxetine)
- Trintellix (vortioxetine)
- Zoloft (sertraline)
What is the safest antidepressant?
Among the newer antidepressants, bupropion and venlafaxine were associated with the highest case fatality rates. In addition, among SSRIs, citalopram and fluvoxamine appeared to be related to higher mortality rates in overdose, whereas fluoxetine and sertraline were the safest .
Does your brain go back to normal after antidepressants?
The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.
How long is too long to be on antidepressants?
Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you’ve had three or more recurrences of depression, make that at least two years.
Do antidepressants affect memory?
Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory.
Can long term use of antidepressants cause dementia?
New evidence shows some anti-depressants can raise dementia risk. Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer’s Society and published today in the British Medical Journal.