Question: Can antidepressants cause fluid retention?

It’s also possible that sertraline and other SSRIs may block the effects of hormones that control sodium and fluid in your body, resulting in fluid retention. In short, while weight gain is a known side effect of sertraline and several other antidepressants, experts aren’t yet completely sure why.

Which antidepressants cause edema?

There are cases of peripheral edema caused by antidepressants such as tranylcypromine, phenelzine, isocarboxazid, escitalopram, sertraline, mirtazapine, and trazodone reported in the relevant literature6-8.

Do antidepressants make you puffy?

Weight gain is a possible side effect of nearly all antidepressants. However, each person responds to antidepressants differently. Some people gain weight when taking a certain antidepressant, while others don’t.

Why do antidepressants make you gain weight?

Antidepressants interfere with serotonin, the neurotransmitter that regulates anxiety and mood while also controlling appetite. In particular, these changes may increase cravings for carbohydrate-rich foods, such as bread, pasta, and desserts. When people are depressed, their appetites are affected.

Can SSRIs cause swelling?

In addition to side effects, antidepressants can also cause allergic reactions in some people. Seek immediate medical treatment if you notice any symptoms of a severe allergic reaction, such as difficulty breathing or swelling in your face, tongue, or throat.

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Which antidepressants cause leg swelling?

Edema has been reported during treatment with various antidepressants such as mirtazapine, trazodone, tranylcypromine, phenelzine and isocarboxazid 13. Kutscher EC, Lund BC, Hartman BA. Peripheral edema associated with mirtazapine.

Why do antidepressants cause fluid retention?

It’s also possible that sertraline and other SSRIs may block the effects of hormones that control sodium and fluid in your body, resulting in fluid retention. In short, while weight gain is a known side effect of sertraline and several other antidepressants, experts aren’t yet completely sure why.

Which antidepressant helps you lose weight?

Bupropion is an antidepressant that may lead to weight loss in some people.

Which antidepressant is least likely to cause weight gain?

Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Amitriptyline and nortriptyline are older drugs.

How can I avoid gaining weight on antidepressants?

As simple as it may sound, the best chance of avoiding, or lessening further, undesirable weight gain when taking a prescribed antidepressant or antipsychotic medication, is to simultaneously participate in a formal weight management program.

Do you gain weight on anxiety medication?

Experts say that for up to 25% of people, most antidepressant medications — including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Lexapro, Paxil, Prozac, and Zoloft — can cause a weight gain of 10 pounds or more.

Do SSRI make you gain weight?

Although some SSRIs are associated with weight loss at first, long-term use of SSRIs is mostly linked to weight gain. Long-term use is considered treatment that lasts longer than six months. Of the SSRIs listed above, paroxetine is most commonly associated with weight gain with both long-term and short-term use.

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