Sertraline Does not Temper Depression in Patients with Chronic Kidney Disease. NEW YORK (Reuters Health) – Sertraline treatment does not relieve depressive symptoms in patients with chronic kidney disease (CKD) who are not on dialysis, according to results from the CAST randomized trial.
Can sertraline cause kidney damage?
This drug may also decrease your kidney function, making your kidney disease worse. For people with liver problems: If you have liver problems or a history of liver disease, your body may not be able to process this drug as well.
Is sertraline safe for kidney disease?
Sertraline is a selective serotonin reuptake inhibitor, or SSRI. Patients with advanced CKD are at significantly increased risk for developing depression and as well as serious complications of kidney disease, she added.
Are antidepressants bad for kidneys?
A: Any medication, if taken without consultation with your physician, can cause kidney damage. It is frequently combinations of medication, both prescribed and over the counter that cause kidney damage.
What antidepressant is safe for kidneys?
Therefore, all SSRIs can be considered in patients with ESRD. Most SSRIs require no renal dose adjustment, except for sertraline which should be reduced to 25 mg/day on initial dosing (17).
What is the side effect of taking sertraline?
Nausea, dizziness, drowsiness, dry mouth, loss of appetite, increased sweating, diarrhea, upset stomach, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Why should you not take sertraline on a night?
Many people who experience nausea and other side effects from sertraline opt to take it at night in order to limit these side effects. Since sertraline can interfere with sleep in a small percentage of users, many people also opt to take sertraline in the morning.
Can sertraline damage your liver?
Rare instances of acute liver failure have been attributed to sertraline therapy. Rechallenge usually results in recurrence of liver injury and should be avoided. Persons with intolerance to sertraline may have similar reactions to other SSRIs and careful monitoring is warranted if other such agents are used.
Is trazodone hard on kidneys?
There are no data available concerning the pharmacokinetic disposition of trazodone or its metabolites in patients with renal and/or liver disease. Therapy with trazodone should be administered cautiously in patients with significantly impaired renal or hepatic function.
What are side effects of sertraline 50 mg?
Sertraline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- difficulty falling asleep or staying asleep.
- dry mouth.
- loss of appetite.
How can I make my kidney strong?
Here are some tips to help keep your kidneys healthy.
- Keep active and fit. …
- Control your blood sugar. …
- Monitor blood pressure. …
- Monitor weight and eat a healthy diet. …
- Drink plenty of fluids. …
- Don’t smoke. …
- Be aware of the amount of OTC pills you take. …
- Have your kidney function tested if you’re at high risk.