FDA Admits that Generic Wellbutrin is Less Effective than Brand Name. The U.S. Food and Drug Administration (FDA) finally has admitted that the generic of the popular antidepressant Wellbutrin XL is not as effective as GlaxoSmithKline’s original drug.
Is there a difference between Wellbutrin and generic bupropion?
The generic name for the drug is bupropion. Bupropion is an antidepressant medication that works by changing the levels of chemicals in the brain. There is no difference in strength between Wellbutrin XL and SR. The difference lies in how you take your dose.
Who makes brand name Wellbutrin?
But GlaxoSmithKline (GSK) has taken the name game a step further with bupropion. At last count, it had given the drug 4 different names. It was first marketed as the antidepressant Wellbutrin, and then relaunched as Zyban, a smoking-cessation aid.
What is the best alternative to Wellbutrin?
- Wellbutrin (bupropion) Prescription only. …
- 10 alternatives.
- Buspar (buspirone) Prescription only. …
- Cymbalta (duloxetine) Prescription only. …
- Celexa (citalopram) Prescription only. …
- Zoloft (sertraline) Prescription only. …
- Remeron (mirtazapine) Prescription only. …
- Oleptro (trazodone) Prescription only.
Why was Wellbutrin discontinued?
The decision is based on an FDA study that found that the extended release (XL) form of bupropion — Budeprion XL — at the 300 milligram (mg) dose was not bioequivalent to brand-name Wellbutrin XL at the same dose, suggesting that it may not be as safe and effective.
How does bupropion make you feel?
What Are The Possible Side Effects Of Bupropion? Headache, weight loss, dry mouth, trouble sleeping (insomnia), nausea, dizziness, constipation, fast heartbeat, and sore throat. These will often improve over the first week or two as you continue to take the medication.
Why does bupropion smell bad?
Cysteine reacts with the free-radicals before they can react with the bupropion, increasing the medication’s shelf-life. Degradation of cysteine can produce hydrogen sulfide, ammonia, and acetaldehyde;6 all compounds which have foul aromas, two due to the presence of amine groups or sulfur.
Does bupropion XL make you lose weight?
Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more.
Is bupropion a stimulant?
“It is a stimulant drug,” he told CTV News Channel about bupropion. “It’s in the same family as amphetamines and methamphetamines.” Long explains that Wellbutrin and other bupropion medications typically come in controlled-release pills, which allows the medication to enter the bloodstream slowly.
Which Wellbutrin is best for weight loss?
Bupropion seems to be effective for weight-loss maintenance as well. A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012).
What is the generic brand for Wellbutrin?
The generic for Wellbutrin SR is bupropion SR, and the generic for Wellbutrin XL is bupropion XL. All of these products need a prescription, and the prescription must note which version you need. If not, your pharmacist will likely question it.