How do antidepressants treat migraines?

Tricyclic antidepressants, such as amitriptyline, are most effective and likely work by affecting the level of serotonin and other chemicals in your brain.

Which antidepressant is best for migraines?

Recent findings: Antidepressants are commonly used as migraine preventives. Amitriptyline has the best evidence for use in migraine prevention. Nortriptyline is an alternative in patients who may not tolerate amitriptyline. The sedating effect of TCAs can be beneficial for patients with comorbid insomnia.

Does zoloft help migraines?

Selective serotonin reuptake inhibitors, such as fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) work well for depression and anxiety, but lack strong evidence supporting effectiveness as migraine preventives. Nutritional Supplements, Vitamins, and Minerals.

Can anxiety medication help migraines?

Medication. depression and anxiety problems are types of drugs called SSRIs and SNRIs. While good for depression and anxiety, they are not particularly effective for headache. Your doctor can look at your symptoms, and help find the best type of medication or combination of medication for you.

Can migraines be caused by depression?

Depression can either cause a headache or become a related complication of frequent headaches, such as migraine. In either case, it’s important to identify your depression symptoms so you can seek treatment.

How does serotonin affect migraines?

Various studies have implicated serotonin in the pathogenesis of migraine. Serotonin vasoconstricts the nerve endings and blood vessels and in this way affects nociceptive pain. Comings43 postulated that low serotonin levels dilate blood vessels and initiate migraine.

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Can antidepressants give you migraines?

When you first begin antidepressant treatment, depression medication side effects can be physical symptoms like headache, joint pain, muscle aches, nausea, skin rashes, or diarrhea. These symptoms are usually mild and temporary.

Do triptans help depression?

Because migraine is “co-morbid” with depression (ie, each disorder occurs more frequently in individuals afflicted by the other condition than it does in the general population), many patients may be prescribed both a triptan (for acute migraine treatment) and an SSRI or SNRI (for chronic treatment of depression).

Can antihistamines help migraines?

Relieving your allergies–with nasal steroids, antihistamines, or allergy shots–may improve any headache symptoms that accompany them.

How long can a migraine last?

A migraine usually lasts from 4 to 72 hours if untreated. How often migraines occur varies from person to person. Migraines might occur rarely or strike several times a month.

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