Does Trazodone contribute to dementia?

Analysis revealed that the incidence of dementia was higher among trazodone users than that among matched antidepressant users (1.8 vs. 1.1 dementia cases per 100 person-years). The risk for dementia was also higher for trazodone users compared with other antidepressant users (HR = 1.8; 95% CI, 1.56-2.09).

Is trazodone linked to dementia?

Conclusions. In this study of UK population-based electronic health records, we found no association between trazodone use and a reduced risk of dementia compared with other antidepressants. These results suggest that the clinical use of trazodone is not associated with a reduced risk of dementia.

Can trazodone cause memory loss?

Trazodone produced small but significant impairments of short-term memory, verbal learning, equilibrium, and arm muscle endurance across time points.

Does trazodone prevent dementia?

Although evidence links decreased sleep quality and depression to cognitive decline or Alzheimer’s disease, there is no evidence that long-term or short-term treatment of trazodone prevents dementia. Concerns were raised that trazodone may affect cognition function.

Is trazodone bad for your brain?

Trazodone does not generally cause cognitive impairment or daytime sleepiness. This is unlike many other medicines used for sleep. Trazodone has also been shown to increase deep sleep. Other research shows that worse sleep is associated with brain changes also seen in AD, and with worse cognitive function and dementia.

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Is it OK to take trazodone daily?

If you have had depression more than once, your doctor may recommend carrying on with trazodone for much longer. Is it safe to take it for a long time? Yes, trazodone is safe to take for a long time. There do not seem to be any lasting harmful effects from taking it for many months, or even years.

Is it safe to take trazodone every night?

The AASM 2017 guidelines for doctors using medication to treat chronic insomnia do not recommend trazodone because there’s so little data to support its use. The American College of Physicians also does not recommend trazodone in its 2021 insomnia treatment guidelines.

What are the long term side effects of trazodone?

Trazodone Long Term Side Effects

  • Decreased serum sodium levels (hyponatremia) and associated symptoms (headache, concentration problems, memory problems, confusion, weakness, unsteadiness, increased fall risk).
  • Serotonin syndrome.
  • Confusion.
  • Angle-closure glaucoma.
  • Blurred vision.
  • Hypotension.
  • Fainting.

Is trazodone safe for seniors?

Trazodone has been shown to be effective in the elderly population mainly due to associated reduced anticholinergic effects and undetectable electrocardiographic changes. Another important aspect of this drug is its good tolerability as a treatment for depression in elderly patients.

What is the number one food that fights dementia?

Researchers developed the diet by looking at the Mediterranean and DASH diets, then focusing on the foods with the most compelling findings in dementia prevention. Vegetables, especially leafy greens, rose to the top. In general, fruit didn’t, though berries made the list.

What are some side effects of trazodone?

Trazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache.
  • nausea.
  • vomiting.
  • bad taste in mouth.
  • diarrhea.
  • constipation.
  • changes in appetite or weight.
  • weakness or tiredness.
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Psychoactive drugs and substances