Quetiapine is an atypical antipsychotic agent with minimal propensity to induce hyperprolactinemia in standard therapeutic dosages. Despite that quetiapine is considered to be a prolactin-sparing atypical antipsychotic, hyperprolactinemia with related side effects may rarely be encountered in susceptible individuals.
Does Seroquel increase prolactin levels?
A study on the incidence of hyperprolactinemia and prolactin-related side effects in children and adolescents treated with antipsychotics showed that there is no significant increase in prolactin level after the long-term use (2 years) of quetiapine.
What medications can cause high prolactin levels?
The medications that most commonly cause hyperprolactinemia are antipsychotic agents; however, some newer atypical antipsychotics do not cause this condition. Other classes of medications that cause hyperprolactinemia include antidepressants, antihypertensive agents, and drugs that increase bowel motility.
Can quetiapine cause raised prolactin?
Although atypical antipsychotic agents, such as olanzapine, quetiapine, and clozapine, have shown to increase prolactin level, this effect is minimal and short-lived.
What antipsychotics do not increase prolactin?
Now we know that atypical antipsychotics such as clozapine, olanzapine, quetiapine, sertindole, and ziprasidone are not associated with significant prolactin increase.
Does Seroquel lower prolactin levels?
Quetiapine causes less prolactin elevation and/or galactorrhoea than other atypical antipsychotics.
Can Abilify increase prolactin?
Hence, in the absence of a competing D2 antagonist and the presence of dopamine (the natural agonist), aripiprazole could act as a functional antagonist and thus elevate prolactin levels.
How can I get my prolactin levels down?
Treatment for high prolactin levels
- changing your diet and keeping your stress levels down.
- stopping high-intensity workouts or activities that overwhelm you.
- avoiding clothing that makes your chest uncomfortable.
- avoiding activities and clothing that overstimulate your nipples.
- taking vitamin B-6 and vitamin E supplements.
Can high prolactin be treated?
Oral medications often can decrease the production of prolactin and eliminate symptoms. Medications may also shrink the tumor. However, long-term treatment with medications is generally necessary. Doctors use drugs known as dopamine agonists to treat prolactinoma.
What are the symptoms of high prolactin?
High Prolactin Level Symptoms
- White milk leaking from nipples.
- Absent, infrequent, or irregular periods.
- Loss of libido.
- Painful or uncomfortable intercourse.
- Vaginal dryness.
- Excessive body and facial hair growth (hirsutism)
When do you repeat prolactin?
Prolactin levels should be repeated after 4 weeks of starting therapy and then repeated only after 3-6 months depending on symptom reversal. Repeat MRI is done after 6 months of normalization of prolactin levels.
What happens when prolactin is high?
Excess prolactin can cause the production of breast milk in men and in women who are not pregnant or breastfeeding. In women, too much prolactin can also cause menstrual problems and infertility (the inability to get pregnant). In men, it can lead to lower sex drive and erectile dysfunction (ED).