The multireceptor pharmacologic profile of asenapine includes antagonism at serotonergic 5-HT2A and adrenergic α2 receptors , suggesting that it may effectively treat depressive symptoms.
Is Saphris a mood stabilizer?
SAPHRIS (asenapine) is a prescription medicine used for: Acute treatment of manic or mixed episodes of bipolar I disorder when used alone in adults or children (ages 10-17) Acute treatment of manic or mixed episodes of bipolar I disorder when used with a mood stabilizer (lithium or valproate) in adults.
How does Saphris make you feel?
Drowsiness, dizziness, lightheadedness, and weight gain may occur. Numbness/tingling of the mouth may also occur but usually goes away within 1 hour. Sores, blisters, or pain under the tongue may rarely occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What does Saphris do to the brain?
Asenapine is a medication that works in the brain to treat schizophrenia. It is also known as a second generation antipsychotic (SGA) or atypical antipsychotic. Asenapine rebalances dopamine and serotonin to improve thinking, mood, and behavior.
Can Saphris cause anxiety?
Tell your doctor right away if you notice any of the following side effects: feelings of anxiety/agitation/jitteriness, drooling/trouble swallowing, restlessness/constant need to move, shaking (tremor), shuffling walk, stiff muscles, severe muscle spasms/cramping (such as twisting neck, arching back, eyes rolling up), …
How quickly does Saphris work?
Based on the available evidence, asenapine is efficacious in the treatment of acute mania, including in the treatment of mixed episodes. Treatment gains become apparent at day 2, but are more prominent at week 3 and thereafter.
Is Saphris addictive?
Ask your doctor if you have any questions about why SAPHRIS has been prescribed for you. SAPHRIS is not addictive. This medicine is available only with a doctor’s prescription.
Can you stop Saphris cold turkey?
Saphris has no habit-forming potential, but it is not recommended that you discontinue use of the drug before talking with your doctor, as withdrawal symptoms can occur.
Is Saphris and asenapine the same thing?
Saphris (asenapine) is an atypical antipsychotic psychiatric medication used to treat certain mental/mood disorders (such as schizophrenia, bipolar disorder).
Can Saphris be taken once a day?
The US Food and Drug Administration recommended dose for asenapine as the acute treatment of schizophrenia is 5 mg twice daily,3 but its terminal half-life of approximately 24 hours3 suggests that it can be administered as a single bedtime dose.