Ephedrine is a central nervous system stimulant used to treat low blood pressure problems (hypotension).
Does ephedrine affect blood pressure?
Ephedrine produces norepinephrine release, stimulating mostly A1 and B1 receptors; the effects resemble those of epinephrine although they are less intense. Increases in systolic blood pressure, diastolic blood pressure, heart rate, and cardiac output are noted.
Does ephedrine damage your heart?
Ephedra can cause a quickened heartbeat and elevated blood pressure. Side effects include heart palpitations, nausea, and vomiting. More than 800 dangerous reactions have been reported with use of the herb. These include heart attacks, strokes, seizures, and sudden deaths.
How much does ephedrine increase blood pressure?
Results: Ephedrine plus caffeine increased systolic blood pressure (peak difference, 11.7 +/- 9.4 mm Hg; compared with placebo, P =. 0005) and heart rate (peak difference, 5.9 +/- 8.8 beats/min; compared with placebo, P =. 001) and raised fasting glucose, insulin, free fatty acid, and lactate concentrations.
What are the side effects of ephedrine?
Common side effects of Ephedrine usually occur with larger doses and include:
- spinning sensation (vertigo),
- loss of appetite,
- trouble sleeping (insomnia),
Why do athletes take ephedrine?
Because ephedrine is a sympathomimetic and a central nervous system stimulant, it is commonly used as an energy enhancer. Ma huang-containing products are marketed and used to improve aerobic performance and endurance, reduce fatigue, increase alertness, improve reaction time, and even increase strength.
What are the long term effects of ephedrine?
Ephedra can cause severe life-threatening or disabling conditions in some people. Ephedra use is linked to high blood pressure, heart attacks, muscle disorders, seizures, strokes, irregular heartbeat, loss of consciousness, and death.
How long does it take for ephedrine to work?
Onset with intravenous use is fast, while injection into a muscle can take 20 minutes, and by mouth can take an hour for effect. When given by injection it lasts about an hour and when taken by mouth it can last up to four hours.
How does ephedrine act on the body?
Ephedrine is a sympathomimetic amine that activates adrenergic receptors, increasing heart rate and blood pressure, and causing bronchodilation. The therapeutic window is wide as patients can be given doses of 5mg up to 50mg.
What is the difference between ephedra and ephedrine?
Ephedrine is a chemical contained in the ephedra herb. Ephedrine has medical uses, mostly in operating rooms and intensive care units. Its chemical properties raise blood pressure and heart rate and open up the large air passages in the lungs.
Can you overdose on ephedrine?
The symptoms of overdose are normally seen as nausea, vomiting, hypertension, fever, palpitations, tachycardia, restlessness, respiratory depression and convulsions. Paranoid psychosis, delusions and hallucinations may also follow ephedrine overdosage.
Is ephedrine a decongestant?
Ephedrine is a decongestant and bronchodilator used for the temporary relief of mild, intermittent asthma symptoms, including shortness of breath, chest tightness, and wheezing.
Does ephedrine deplete?
Large parenteral doses of ephedrine may cause confusion, delirium, hallucinations, or euphoria. Ephedrine may deplete norepinephrine stores in sympathetic nerve endings and tachyphylaxis to the cardiac and pressor effects of the drug may develop.