Trazodone can cause a severe allergic reaction. Symptoms can include: trouble breathing.
Does trazodone lower oxygen levels?
Measurements and Main Results: Compared with placebo, trazodone resulted in a significant reduction in AHI (38.7 vs. 28.5 events/h, P = 0.041), without worsening oxygen saturation or respiratory event duration. Trazodone was not associated with a significant change in the non-REM arousal threshold (−20.3 vs.
What are the most common side effects of trazodone?
Trazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- bad taste in mouth.
- changes in appetite or weight.
- weakness or tiredness.
Can trazodone worsen sleep apnea?
Rationale: A low respiratory arousal threshold is a physiological trait involved in obstructive sleep apnea (OSA) pathogenesis. Trazodone may increase arousal threshold without compromising upper airway muscles, which should improve OSA.
Can trazodone cause chest tightness?
Get medical help right away if you have any very serious side effects, including: chest/jaw/left arm pain, fainting, fast/irregular heartbeat, seizures. This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity.
Does trazodone slow down your breathing?
Trazodone, a serotonin antagonist and reuptake inhibitor, is the most commonly used sedative in the United States. Trazodone has been shown to reduce breathing disturbances without impairing upper airway muscle activity in an English bulldog model of OSA.
Is it OK to take trazodone every night?
Yes, trazodone is safe to take for a long time. There do not seem to be any lasting harmful effects from taking it for many months, or even years. Some people need to take trazodone long term to treat depression or anxiety that keeps coming back.
What medications should not be taken with trazodone?
Drugs you should not use with trazodone
Examples of these drugs include: Monoamine oxidase inhibitors (MAOIs), such as isocarboxazid, phenelzine, tranylcypromine, or selegiline. You shouldn’t take trazodone with MAOIs or within 14 days of taking them. Taking these drugs together raises your risk for serotonin syndrome.
Can trazodone affect memory?
Trazodone produced small but significant impairments of short-term memory, verbal learning, equilibrium, and arm muscle endurance across time points.
Is trazodone a bad drug?
Trazodone can also cause heart rhythm disorders. And some evidence suggests that it can cause priapism, or persistent erection, a medical emergency that may require surgery and can lead to impotence if not treated promptly.
How long does trazodone last for sleep?
The blocking of the 5-HT2A, histamine H1, and alpha receptors is thought to produce the hypnotic effect reported for low doses of trazodone (25–100mg). At these low doses, trazodone induces and maintains sleep without causing daytime drowsiness or tolerance, mainly because of its short half-life (3–6 hours).
Does trazodone affect your heart?
Trazodone may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
Does trazodone cause congestion?
Nausea, vomiting, diarrhea, drowsiness, dizziness, tiredness, blurred vision, changes in weight, headache, muscle ache/pain, dry mouth, bad taste in the mouth, stuffy nose, constipation, or change in sexual interest/ability may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What are the long term side effects of trazodone?
Trazodone Long Term Side Effects
- Decreased serum sodium levels (hyponatremia) and associated symptoms (headache, concentration problems, memory problems, confusion, weakness, unsteadiness, increased fall risk).
- Serotonin syndrome.
- Angle-closure glaucoma.
- Blurred vision.