SSRIs can reduce the ability of platelets to clot, can decrease the platelet count, and have been associated with bleeding in the stomach.
What medications cause low platelets?
Heparin, a blood thinner, is the most common cause of drug-induced immune thrombocytopenia.
Other medicines that cause drug-induced thrombocytopenia include:
- Gold, used to treat arthritis.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
Do SSRIs lower platelets?
Some medications impair platelet function, leading to increased bruising and bleeding. SSRIs decrease an important platelet component called serotonin, which may cause bleeding in some patients. SSRIs include fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine (Luvox) and citalopram (Celexa).
What is the most common cause of low platelet count?
Factors that can decrease platelet production include: Leukemia and other cancers. Some types of anemia. Viral infections, such as hepatitis C or HIV.
Does Lexapro affect platelets?
Decrease in platelet count on escitalopram was significant, while the others were not. These findings suggest that escitalopram may be associated with decreased platelet count, and bupropion is less likely to exert an influence on platelet count.
How low can platelets go before death?
When the platelet count drops below 20,000, the patient may have spontaneous bleeding that may result in death. Thrombocytopenia occurs due to platelet destruction or impaired platelet production.
When should I be concerned about low platelet count?
Talk to your doctor immediately if you experience any signs of internal bleeding. Rarely, this condition may lead to bleeding in your brain. If you have a low platelet count and experience headaches or any neurological problems, tell your doctor right away.
How does serotonin affect platelets?
Serotonin is transported by platelets and released upon activation. This induces constriction of injured blood vessels and enhances platelet aggregation to minimize blood loss.
Can trazodone cause low platelets?
Bleeding: Trazodone may cause a reduced number of platelets in the blood, which can make it difficult to stop cuts from bleeding. If you notice any signs of bleeding, such as frequent nosebleeds, unexplained bruising, or black and tarry stools, notify your doctor as soon as possible.
Do SSRIs thin your blood?
The researchers looked at the records of more than 27,000 patients aged 50 and over between 1997 and 2007, and found taking an SSRI and Aspirin increased risk of a bleed by 1.42 times. And taking an SSRI with combined blood thinning therapy — Aspirin plus clopidogrel — pushed the risk up to 1.57 times.
How do I raise my platelet count?
These tips can help you understand how to raise your blood platelet count with foods and supplements.
- Eating more leafy greens. …
- Eating more fatty fish. …
- Increasing folate consumption. …
- Avoiding alcohol. …
- Eating more citrus. …
- Consuming more iron-rich foods. …
- Trying a chlorophyll supplement.
Is a platelet count of 130 bad?
Platelet count Platelets help stop bleeding by sticking together to form blood clots, which “plug” cuts. A normal platelet count range is 140 to 400 K/uL. Sometimes, your CBC may show that your counts or values are too low.