No instances of acute liver failure or chronic liver injury have been linked to phentermine/topiramate, but it has had limited general clinical use. References on the hepatotoxicity and safety of phentermine and topiramate separately are given in the sections on the individual agents.
Can phentermine increase liver enzymes?
Hepatotoxicity. Phentermine has not been linked to an increased rate of serum enzyme elevations during therapy; however, results of ALT monitoring during phentermine therapy have rarely been reported.
Do diet pills affect your liver?
Weight loss supplements were linked to even worse damage — inflammation of the liver that in some cases could have been fatal without a liver transplant, he says. In the study, 12% of the 17 people taking weight loss products needed a transplant.
Does phentermine go through liver?
Phentermine may be partially metabolized in the liver.
Can phentermine cause long term damage?
Phentermine, especially when combined with fenfluramine, has been associated with high pressures in the pulmonary arteries (pulmonary hypertension) and defects in heart valves, both serious complications. Physical and psychological dependence may occur with the long-term use of phentermine.
Can you take 2 phentermine a day?
Do not take two doses at one time. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phentermine can be fatal.
Can phentermine affect your kidneys?
Phentermine can cause elevation of the blood pressure and this can hasten the deterioration of kidney function.
What supplements are bad for the liver?
In fact, some common herbs could cause toxic liver disease. Watch out for supplements that contain aloe vera, black cohosh, cascara, chaparral, comfrey, ephedra, or kava.
What medications should be avoided with liver disease?
The 10 Worst Medications for Your Liver
- 1) Acetaminophen (Tylenol) …
- 2) Amoxicillin/clavulanate (Augmentin) …
- 3) Diclofenac (Voltaren, Cambia) …
- 4) Amiodarone (Cordarone, Pacerone) …
- 5) Allopurinol (Zyloprim) …
- 6) Anti-seizure medications. …
- 7) Isoniazid. …
- Azathioprine (Imuran)
What vitamins are bad for your liver?
Specific examples of hepatotoxicity are given in the sections on vitamin A and niacin.
- Folic Acid (Folate, Folinic Acid)
- Vitamin A & Retinoids. Vitamin A. …
- Vitamin B. Biotin (B5) …
- Vitamin C (Ascorbic Acid)
- Vitamin D (Cholecalciferol, Ergocalciferol)
- Vitamin E (alpha Tocopherol)
- Vitamin K (Menadione, Phytonadione)
Does phentermine cause heart issues?
These include stroke, arrhythmia (irregular heartbeat), heart failure, coronary artery disease, valve disease, and uncontrolled high blood pressure. Phentermine may cause a serious increase in your blood pressure. This may make your heart work harder. The extra stress on your heart may make your heart disease worse.
Why would my liver enzymes be high?
Elevated liver enzymes often indicate inflammation or damage to cells in the liver. Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, elevating liver enzymes on blood tests.
How long can you safely take Adipex?
Adipex (phentermine) is a prescription medication given to assist people with weight loss. It works by decreasing the appetite and is usually prescribed for three to six weeks (though can be used for up to 12 weeks) to people who are exercising and eating a low-calorie diet.