Are SSRIs safe long term?

SSRIs are generally considered safe to take long-term, says Maurizio Fava, executive vice chair of the department of psychiatry at Massachusetts General Hospital.

Do SSRIs have permanent effects?

Long-term antidepressant users are risking permanent damage to their bodies, according to leading medical experts. Dr Tony Kendrick, a professor of primary care at the University of Southampton, says more urgent action needs to be taken to encourage and support long-term users to come off the medication.

Can SSRIs damage your brain?

“Perhaps we should be a bit more cautious than we are at the moment, about who we use antidepressants for. We need more research.” He notes, however, that SSRI’s have been in use for some 25 years and there is no evidence of brain damage or a negative impact on intellectual capacity.

Is long-term antidepressant use harmful?

Patients who have taken antidepressants for years should consider coming off the medication. However, researchers say they will likely face difficult and even dangerous withdrawal symptoms due to a physical dependence.

How long can you use SSRIs?

Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you’ve had three or more recurrences of depression, make that at least two years.

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Does the brain heal after antidepressants?

The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.

Do SSRIs change your personality?

Fact: When taken correctly, antidepressants will not change your personality. They will help you feel like yourself again and return to your previous level of functioning.

What is the safest antidepressant?

Among the newer antidepressants, bupropion and venlafaxine were associated with the highest case fatality rates. In addition, among SSRIs, citalopram and fluvoxamine appeared to be related to higher mortality rates in overdose, whereas fluoxetine and sertraline were the safest [188].

How long after stopping antidepressants before I feel normal again?

In studies on adults with moderate or severe depression, 40–60% report improvements within 6–8 weeks. Those who wish to come off antidepressants because they feel better should ideally wait for at least 6–9 months after complete symptom remission before stopping their medication.

Can long term use of antidepressants cause dementia?

New evidence shows some anti-depressants can raise dementia risk. Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer’s Society and published today in the British Medical Journal.

What happens when you stop taking SSRIs?

It might seem like you don’t need the medication anymore, but if you stop taking it, the medicine will leave your body and your symptoms might return. Quitting without consulting your doctor can be life-threatening. Suicide is a serious concern. It can also trigger withdrawal symptoms and relapse of your depression.

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What is the hardest antidepressant to come off of?

Hardest-to-Stop Antidepressants

  • citalopram) (Celexa)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)
  • sertraline (Zoloft)

Can Ssris permanently change brain?

Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function.

Can you take Ssris for life?

MYTH: Once on antidepressants, I’ll be on them for life. FACT: Not true. A general rule clinicians often use is that a person should be treated with antidepressants at least one-and-a-half times as long as the duration of the depressive episode before they can begin to be weaned off.

Psychoactive drugs and substances