What's the recommended dosage of adrafinil?
The adrafinil dosage originally used to treat narcolepsy is 0.6 - 1.2 grams (or 600 - 1,200 mg). Taking adrafinil daily in two divided doses (one in the morning and one in the afternoon) is a good strategy to minimize side effects. Note that taking adrafinil too late in the day (e.g., after 2 pm) may be undesireable because it can impair sleep quality. Adrafinil is a wakefulness-promoting agent that can make it difficult to fall asleep.
Despite the above quoted adrafinil dosage of 600 - 1,200 mg, I actually recommend starting with a lower dose to see how you respond. You can always titrate upwards if necessary. Some people may be sensitive to adrafinil or are prone to the anxiogenic (anxiety-provoking) effects of adrafinil.
How to Dose Adrafinil Powder
Many people choose to take adrafinil powder instead of encapsulated adrafinil. Buying nootropic powders has many advantages. It is often cheaper to purchase adrafinil powder and you’re better able to inspect what you get.
Nootropic powders are typically packaged with a 0.15cc scoop. One 0.15cc scoop delivers a dose of about 80 mg of adrafinil. So 7.5 scoops of 0.15cc adrafinil will furnish a dose of 600 mg of adrafinil. This dosage is the lower bound of the recommended adrafinil range. Despite these approximations, it’s always best to use a scale. That’s because powder density can vary which makes measuring nootropic powders by volume potentially unreliable.
However, adrafinil is relatiely safe in overdose (as is modafinil). So making an error measuring a dosage might make you very uncomfortable (and result in anxiety), but is highly unlikely to result in bodily harm.
What's The Recommended Adrafinil Dosage Based On?
The quoted dosage of 600-1200 mg is based on the original prescribing information for Olmifon (adrafinil). Olmifon is the prescription version of adrafinil originally marketed in Europe. The Olmifon package insert reads as follows:
CompositionAdrafinil; Corn starch, modified sodic carboxymethyl-cellulose, polyvidone excipient, glycerol, magnesium steate, talc, lactose, polyoxyethylene glycol 4000, titanium dioxide, polymethly acrylate glycerol.
Information for the UserThis product is a psycotonic. It is recommended for elderly patients who have difficulty staying alert and who suffer from a general slowing down of mental activity.
- The effectiveness of Olmifon® has not yet been tested on the non-elderly.
- This preparation contains an active ingredient, which could induce a positive result in anti-doping tests for athletes.
CautionIf you suffer from epilepsy, or serious hepatic or renal disorders, consult your doctor before taking this product. Do not hesitate to seek advice from your doctor or chemist, if there is any chance of an interaction-taking place between different medicines. Any additional treatment should be reported, especially if you are taking neuroepileptic medicines. Keep this and all other medicines safely out of the reach of children.
Side EffectsAs with any active product, this medicine may possibly cause side effects. Headache, stomach pains and skin irritations have been reported in clinical tests, and in certain cases, inner tension.
Directions2 to 4 tablets daily. Please follow your doctor’s instructions.
Prescription ConditionsThis product has been prescribed for you in order to remedy a particular medical problem. Do not use it to treat other ailments. Do not use it again without first consulting your doctor. Do not use it to treat another person. Consult your doctor.
Adrafinil Has Fallen Into Disuse Clinically, But Remains Popular As A Supplement
Note that adrafinil is no longer used clinically for the treatment of narcolepsy because it’s been superseded by modafinil.
Modafinil is the more appropriate drug because adrafinil is just a precursor to modafinil.
Upon ingestion, adrafinil is metabolized to adrafinil. Therefore, taking adrafinil instead of modafinil is a more roundabout (and less efficient) way to ingest modafinil. There’s some rumors floating around that adrafinil may be harder on the liver than modafinil but this speculation is essentially unfounded. Both adrafinil and modafinil are vary rarely associated with hepatotoxicity (injury to the liver). But there’s no evidence that adrafinil is more likely to cause this adverse effect.
Adrafinil is a prodrug for modafinil, which means that it’s converted to modafinil in vivo (in the body). However, this conversion is not 100% efficient; not all adrafinil is converted modafinil. Thus a larger dose of adrafinil is needed to produce the same effect as modafinil.
How To Take Adrafinil
- We recommend buying adrafinil from Nootropics Depot.
- You should avoid taking adrafinil at night since it is a wakefulness-promoting agent that will impair sleep quality. It’s best to take adrafinil in the morning or late afternoon.
- The suggested dose of adrafinil is 600 - 1,200 mg, according to the original prescribing information for Olmifon (adrafinil).
- Avoid using adrafinil as a way to function on fewer hours of sleep. Adrafinil might subjectively make you feel more alert and sharp with less sleep. But the reality is that sleep is restorative and essentially for memory consolidation.
- Modafinil is superior to adrafinil, but a little more difficult to obtain without a prescription. If you have access to both adrafinil and modafinil you should use modafinil since lower doses are required and it’s a more efficient drug.
- The physical appearance of adrafinil is as follows: it looks like a whitish-orange powder. It’s best to buy adrafinil from vendors that have well-established quality control practices and are willing to provide you with an independent certificate of analysis (e.g., from Colmaric Analyticals).